عنوان مقاله [English]
The sponge Gelliodes carnosa were sample from offshore Bushehr in the depth of 5-6m and flavonoid compounds extract from them with standard methods. This component were examined against fourteen microorganisms Staphylococcus aureus (PTCC 1189), Bacillus subtilis (PTCC 1156), Escherichia coli (PTCC 1763), Pseudomonas aeroginosa (PTCC 1310) ،Proteus mirabilis(PTCC 1076), Candida albicans (PTCC 5027), Fusarium solani (PTCC 5248), Aspergillus niger (PTCC 5223), Serattia marcescens, Klebsiella pneumonia, Saprolegnia parasitica, Saprolegnia sp., Fusarium sp.1. and Fusarium sp2. Results showed that this compounds presented activity against 58% of pathogens. Antibacterial activity of flavonoid compounds was more than antifungal activity. A Garm negative bacterium was more resistance than garm positive bacteria. The range of created halos was between 9-14mm. Among the tested microorganisms, the B. subtilis and P. mirabilis had the highest sensitivity towards flavonoid compounds respectively whit 14 and 13mm. The growth inhibition of these compounds on the filamentous fungi except saprolegnia was weak. Based on the present finding, it could be inferred that the Gelliodes carnosa as an source for flavonoid compounds for combat with some microbial diseases.