تجزیه و تحلیل بیزین پارامترهای ژنتیکی برای صفات ایمنی همورال و باقی مانده مصرف خوراک در بلدرچین ژاپنی

نوع مقاله : ژنتیک

نویسندگان

1 گروه علوم دامی، دانشکده کشاورزی، دانشگاه زابل، زابل، ایران

2 دانشکده کشاورزی و صنایع غذایی، دانشگاه کوئینزلند، بریزبین، استرالیا

چکیده

هدف از این مطالعه برآورد پارامترهای ژنتیکی صفات ایمنی هومورال (تیتر آنتی‌ بادی علیه سلول ‌های قرمز خونی گوسفندی (SRBC) و ویروس بیماری نیوکاسل (NDV)) و باقی ­مانده مصرف خوراک از 20 تا 45 روزگی در بلدرچین ژاپنی بود. بدین منظور از تعداد 2492 رکورد صفت باقی ­مانده مصرف خوراک و 5238 رکورد مربوط به صفات ایمنی استفاده شد. پارامترهای ژنتیکی صفات با استفاده از تجزیه و تحلیل تک و دو صفتی از طریق نمونه ‌گیری گیبس برآورد شد. وراثت­ پذیری های برآورد شده برای تیتر آنتی ‌بادی کل (AbT)، تیتر (IgY) ایمونوگلوبولین Y، تیتر (IgM) ایمونوگولوبولین M و تیتر (IgF) ایمونوگولوبولین F برعلیه SRBC به ­ترتیب برابر 0/08، 0/14، 0/02 و 0/24 اما وراثت­ پذیری تیتر آنتی ‌بادی برعلیه (NDV (AbNDV پایین ­تر از برآوردهای آنتی ­ژن (0/05=SRBC  (h2 بود. وراثت­ پذیری باقی ­مانده مصرف خوراک در سنین مختلف در دامنه 0/04 تا 0/07 به ­دست آمد. همبستگی ژنتیکی بین تیتر آنتی‌ بادی کل و IgY مثبت و بالا (0/92) بود. همبستگی ژنتیکی بین RFI با IgM منفی و با سایر ایمونوگولوبولین ‌ها (IgY, AbT, IgF) و NDV مثبت بود. از این مطالعه نتیجه­ گیری می­ شود که انتخاب برای IgF با وراثت ­پذیری 0/24 به ­دلیل داشتن همبستگی ژنتیکی منفی (0/23-) با باقی­ مانده مصرف خوراک موجب بهبود این صفت و کاهش هزینه‌ ها، عمدتاً مرتبط با بحث خوراک و انتخاب از روی فنوتیپ حیوانات، می ‌شود. از طرفی به ­دلیل همبستگی مثبت، متوسط و بالای آن با سایر ایمونوگلوبولین‌ ها (0/80-0/34) انتخاب آن منجر به کاهش پاسخ­ های ایمنی هومورال در بلدرچین نمی ‌شود.

کلیدواژه‌ها

عنوان مقاله [English]

Bayesian analysis of genetic parameters for humoral immune responses and residual feed intake traits in Japanese quail

نویسندگان [English]

  • Mojdeh Mahmoudi Zarandi 1
  • Mohammad Rokouei 1
  • Mehdi Vafaei Valleh 1
  • Ali Maghsoudi 1
  • Nicholas Hudson 2
1 Department of Animal Science, Faculty of Agriculture, University of Zabol, Zabol, Iran
2 School of Agriculture and Food Sciences, The University of Queensland, Brisbane, Australia
چکیده [English]

The aim of this study was to estimate genetic parameters of humoral immune responses (antibody titers against sheep red blood cells (SRBC) and Newcastle Disease Virus (NDV)) and residual feed intake from 20 to 45 days of age in Japanese quail. For this purpose, a total of 2492 records of residual feed intake traits and 5238 records of immune traits were used. The analyses of Genetic parameters of traits were estimated through single and bivariate animal models via Gibbs sampling method. Heritability estimates of total antibody titer (AbT), titer of immunoglobulin Y (IgY), titer of immunoglobulin M (IgM) and titer of immunoglobulin F (IgF) against SRBC were 0.08, 0.14, 0.02 and 0.24, respectively, however, heritability of antibody titer against NDV was lower than estimated of SRBC antigen (h2= 0.05). heritability of RFI in different ages were in ranges of 0.04 to 0.07. genetic correlations estimate between total antibody and IgY were positive and high and was 0.92. The negative genetic correlations were related to IgM with RFI and genetic correlations estimates between RFI and other immunoglobulins (IgY, AbT, IgF) and NDV were positive. As a conclusion, selection for IgF due to its heritability (0.24) and negative genetic correlation (-0.23) with RFI, cause improve in RFI and reduce costs, related mainly to feeding and selecting of animals with phenotyping. On the other hand, due to moderate to high positive genetic correlations (0.34-0.80) were found between IgF and other immunoglobulins, selection of it didn’t lead to decline of humoral immune responses in quail.

کلیدواژه‌ها [English]

  • Humoral Immune
  • Residual Feed Intake
  • Antibody Titer
  • Heritability
  • Genetic correlation
  • SRBC

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فصلنامه محیط زیست جانوری
دوره 12، شماره 3
مهر 1399
صفحه 97-104

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