Comparison of D-Penicillamine and silymarin effects on lead level in the pectoral and quadrate muscles of Pekin ducks

Document Type : Physiology (Animal)

Authors

1 Department of Physiology, Faculty of Modern Sciences and Technologies, Tehran Branch of Medical Sciences, Islamic Azad University, Tehran, Iran

2 Department of Animal Sciences, Faculty of Agriculture, Garmsar Branch, Islamic Azad University, Garmsar, Iran

Abstract

Ducks due to their own curious behavior and diet which includes sludge, materials and objects left on the banks of rivers and swamps. They are prone to chronic forms of lead poisoning. Therefore, the aim of this study was to determine the effect of dipenicillamine and silymarin on lead residue in lead affected duck muscles. To study the effect of dipenicillamine and silymarin on lead residue in lead affected duck muscles, 120 one-day old ducks of Pekin breed into 4 groups of 30 pieces in three replications, including group 1: receiving the basic diet in the whole experimental period, group 2: recievingbasic diet+lead nitrate at a dose of 40 mg/kg (control),group 3: receiving basic diet+lead nitrate at a dose of 40 mg/kg+dipenicillamin at a dose of 20 mg/kg, group 4: receiver of basal diet+lead nitrate at a dose of 40 mg/kg +sage extract at a dose of 300 mg/kg was divided and raised for 60 days. After the end of breeding and slaughter period of ducks according to ethical protocols, sampling of chest and thigh muscles in each slaughtered piece was done. The lead concentration of each sample was measured by atomic absorption spectrophotometry by furnace method. According to the results, dipenicillamine and silymarin with their antioxidant properties, they were able to significantly (p < 0.05) reduce the amount of lead remaining in the thigh and chest muscles.

Keywords

References

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Journal of Animal Environment
Volume 12, Issue 3
June 2020
Pages 441-448

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