Placentome collection from dairy cows for research purposes and its implications for their future reproductive performance

Document Type : (original research)

Authors

1 Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

2 Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, Iran

3 Department of Embryology at Reproduction Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACER, Tehran, Iran

4 Department of Genetics, Reproduction Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACER, Tehran, Iran

10.22034/AEJ.2022.323327.2724

Abstract

Placentome in cattle comprises fetal cotyledon and maternal caruncle and is a vital site for feto-maternal substance exchanges. There are considerable metabolic and hormonal interactions in the placentomes that could affect the body of the fetus and the mother. Despite the importance of this tissue in reproduction of cattle, there are few studies on this tissue probably due to worries about the invasive trait of placentome collection and its implications for the future reproductive performances of the cow. In this study, we described a method of placentome collection from cows and investigated its implications for the cows’ subsequent reproductive performance. In this study, placentomes were collected from six cows within 30 minutes after parturition by using a guitar string and a hygienic protocol. Then, one dose of vitamin K and two doses of B-complex (during two days) were administered and the health status of the cows was monitored for several days. The number of inseminations until conception, the length of open days, the interval between two subsequent parturitions and the health status of the following calf were recorded for each cow. These six cows considered as placentome collected group and their data were compared to 45 cows in the same herd as control group. Cows in the control group had at most 430 days of interval between their two subsequent parturitions and underwent no manipulation. According to the results, general health of the placentome collected cows was not affected after placentomectomy. None of the reproduction related parameters including the number of insemination until conception, the length of open days, the interval between two parturitions and the health status of the calves showed significant difference between the placentome collected group compared to control. However, the interval between the first parturition and the second insemination was significantly shorter in the cows that underwent placentome collection. In this study, we described an easy and efficient method of placentome collection from alive cows and showed that this method does not have considerable implications for the cows’ reproductive performance. Therefore, by careful collection of placentomes and by having justifiable research purposes, placentome collection from the cows could be considered for future studies.

Keywords

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References

  1. Furukawa, S., Kuroda, Y. and Sugiyama, A.A., 2014. Comparison of the Histological Structure of the Placenta in Experimental Animals. Journal of Toxicologic Pathology. 27(1): 11-18. doi: 10.1293/tox.2013-0060.
  2. Reece, W.O., 2015. Dukes’ physiology of domestic animals. (13st). In: Reece WO, editor. Female Reproduction in Mammals. Iowa: Wiley-Blackwell. 675-692.
  3. Carter, A.M., 2000. Evolution of placentation in cattle and antelopes. Animal Reproduction. 16(1): 3-17. doi: 10.21451/1984-3143-AR2018-0145.
  4. Kenneth, M., 1990. Reproductive Pathology of Domestic Mammals. In: Kenneth M. The Uterus: Anatomy. New York: Academic Press. 125-131.
  5. Davies, C.J., Fisher, P.J. and Schlafer, D.H., 2000. Temporal and Regional Regulation of Major Histocompatibility Complex Class I Expression at the Bovine Uterine/Placental Interface. Placenta. 21(2-3): 194-202. doi: 10.1053/plac.1999.0475.
  6. Pfarrer, C., Ebert, B., Miglino, M.A., Klisch, K. and Leiser, R., 2001. The three-dimensional feto-maternal vascular interrelationship during early bovine placental development: a scanning electron microscopical study. Journal of Anatomy. 198: 591-602. doi: 10.1046/j.1469-7580.2001.19850591. x.
  7. Attupuram, N.M., Kumaresan, A., Narayanan, K. and Kumar, H., 2016. Cellular and molecular mechanisms involved in placentalseparation in the bovine: a review. Molecular Reproduction and Development. 83(4): 287-297. doi: 10.1002/mrd.22635.
  8. Pastor-Fernández, I., Collantes-Fernández, E., Jimnez-Pelayo, L., Ortega-Mora, L.M. and Horcajo, P., 2021. Modeling the Ruminant Placenta-Pathogen Interactions in Apicomplexan Parasites: Current and Future Perspective. Frontiers in Veterinary Science. 7: 1-20. doi: 10.3389/fvets. 2020.634458.
  9. McNeel, A.K., Ondrak, J.D. and Cushman, R.A., 2013. Technical Report: Serial collections of placentomes during parturition in cattle and subsequent reproductive performance. Journal of Animal Science. 91(5): 2119-2121. doi: 10.2527/jas.2012-5876.
  10. D'Alessandro, A.J., 1942. Vitamin K and its rôle in blood coagulation. The American Journal of Surgery. 57(1): 104-111. doi: 10.1016/S0002-9610(42)90956-5.
  11. Koury, M.J. and Ponka, P., 2004. New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annual Review of Nutrition. 24: 105-131. doi: 10.1146/ annurev.nutr.24.012003.132306.
  12. Hooshmandabbasi, R., Zerbe, H., Bauersachs, S., de Sousa, N.M., Boos, A. and Klisch, K., 2018. Pregnancy associated glycoproteins in cows with retained fetal membranes. Theriogenology. 105: 158-163. doi: 10.1016/j. theriogenology.2017.09.031.
  13. Kankofer, M., Wiercinski, J. and Zerbe, H., 2000. Activity of Placental β-N-Acetyl-Glucosaminidase in Cows with and without Retained Fetal Membranes. Reproduction in Domestic Animals. 35(3-4): 97-100. doi: 10.1111/rda. 13747.
  14. Sprekeler, N., Kowalewski, M.P. and Boos, A., 2012. TRPV6 and Calbindin-D9k-expression and localization in the bovine uterus and placenta during pregnancy. Reproductive Biology and Endocrinology. 10(66): 1-13. doi: 10.1186/1477-7827-10-66.
  15. Streyl, D., Kenngott, R., Herbach, N., Wanke, R., Blum, H., Sinowatz, F., Wolf, E., Zerbe, H. and Bauersachs, S., Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes. Reproduction. 143(1): 85-105. doi: 10.1530/REP-11-0204.
  16. von Hof, J., Sprekeler, N., Schuler, G., Boos, A. and Kowalewski, M.P., 2017. Uterine and placental expression of HPGD in cows during pregnancy and release of fetal membranes. Prostaglandins & Other Lipid Mediators. 128: 17-26. doi: 10.1016/j.prostaglandins.2016.12.003.
Journal of Animal Environment
Volume 14, Issue 4
February 2023
Pages 65-72

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